NWU - Department of Cell and Molecular Biology

Facilities


The Cell Imaging Facility

The Cell Imaging Facility is a Medical School Shared Facility staffed by a full-time Director (Dr. Teng-Leong Chew) and an EM Technician. The facility provides access to the latest light microscopic technology including laser scanning confocal microscopes, custom multi-photon imaging, and fluorescence correlation spectroscopic analysis on the microscopic level. A variety of other advanced light microscopes, microinjection capabilities, and live cell imaging is available. The facility also has two transmission electron microscopes with microtomes and other ancillary equipment. The staff are available to consult with users to design new assays and imaging modalities.

Northwestern University Biotechnology Laboratory
The primary mission of the Northwestern University Biotechnology Laboratory (NUBL) is to develop and maintain a cost-effective service laboratory that meets the biotechnology needs of Northwestern University. NUBL's goal is to develop the vision and expertise to lead rather than follow in obtaining, using, and providing state-of-the-art instrumentation and methodologies for biological, biomedical, and clinical research. NUBL assists research in small and large laboratories by providing a wide range of fee-for-service analytical methods and access to high tech instrumentation for researcher use.

Robert H. Lurie Comprehensive Cancer Center of Northwestern University 
These facilities provide low-cost media, sera, tissue culture reagents, molecular biology enzymes and kits to researchers and laboratories at Northwestern and affiliated hospitals.

Flow Cytometry
The Flow Cytometry Core Facility provides a comprehensive service for investigators seeking to utilize the technology of flow cytometry to effectively advance their research programs. The laboratory is equipped with state-of-the-art equipment which includes a single-laser bench top flow cytometer (Beckman Coulter XL-MCL) and a multi-laser flow cytometer (Beckman Coulter Elite ESP) which also functions as a droplet cell-sorter. Staffing includes the lab director, lab manager/operator, and a flow cytometry technician.

Keck Biophysics Facility
The Keck Biophysics Facility is an internationally unique resource for the study of the structures and interactions of biological and synthetic macromolecules. This shared research center was created by Northwestern University's Center for Structural Biology with grants from the W.M.Keck Foundation and additional support from NIH, the Rice Foundation, and the Robert H.Lurie Comprehensive Cancer Center.

Targeted Mutagenesis
The primary goal of this facility is to generate chimeric (knock-out) mice by using homologous recombination and embryonic stem (ES) cells for biomedical research conducted by investigators of Northwestern University, Northwestern University Medical School, Children's Memorial Institute for Education and Research (CMIER), and other affiliated institutions.

Analytical Services Laboratory
The Analytical Services Laboratory is a shared facility providing access to most types of chemical analysis instrumentation. It is located on the Evanston campus. NMR spectrometers, mass spectrometers, optical spectrometers, elemental analysis instruments, chromatography instruments, thermal analysis equipment, and X-ray diffractometers are found in this lab. The facility is staffed between 9AM and 5PM weekdays. Samples may be submitted to the staff for analysis or you may run them by yourself after appropriate training.

NMR Facility
NMR Facility at Northwestern is a NIH-funded university-wide shared resource dedicated for Structural Biology research. The Facility comprises a 600 MHz spectrometer, which is housed in the Analytical Services Laboratory (ASL) of the Department of Chemistry. The facility is also equipped with three SGI O2 workstations and an assortment of software and graphics visualization tools for NMR spectral processing and analysis. The workstations are also equipped with software and computing power for NMR structure determination of average-sized proteins, nucleic acids and carbohydrates.

Northwestern University Shared Research Facilities
This comprehensive site provides links to most research facilities at Northwestern that are shared by the many science departments at both the Chicago and Evanston campuses.